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mesoestetic
Intensive night treatment for oily, acne-prone skin with active blemishes, excess sebum and persistent congestion.
mesoestetic blemiderm® Treatment is a corrective cream-gel developed specifically for oily skin with active acne.
The advanced night formula combines Mesoestetic's 10% azelaic-acid technology, liposomal Retinol, Salicylic Acid, Mandelic Acid, Shikimic Acid and blemiclear complex to address several mechanisms associated with persistent blemishes.
Rather than only drying individual spots, it works across congestion, excess sebum, abnormal skin-cell build-up, inflammatory activity and acne-related microbial imbalance, while supporting smoother and more refined-looking skin.
Benefits:10% Azelaic-Acid Technology
Mesoestetic currently describes blemiderm® Treatment as containing 10% Azelaic Acid.
Azelaic-acid technology is particularly relevant to acne-prone skin because of its complementary sebum-regulating, anti-inflammatory, antimicrobial and keratinisation-supporting properties.
Importantly, the current official INCI lists Disodium Azelate, the sodium salt of azelaic acid, rather than free Azelaic Acid.
Chris&Alley therefore retains Mesoestetic's official 10% positioning while avoiding the claim that the INCI contains 10% pure free Azelaic Acid.
Liposomal Retinol
Retinol supports normal epidermal renewal and helps reduce the abnormal accumulation of dead skin cells that can contribute to pore blockage.
Mesoestetic uses a liposomal delivery system to incorporate Retinol within its broader acne-correction strategy.
It also helps improve uneven texture and the appearance of residual post-breakout skin changes.
Salicylic Acid
An oil-soluble beta-hydroxy acid particularly suited to congested and acne-prone skin.
Salicylic Acid helps exfoliate within sebum-rich pores, loosen congestion and improve the appearance of blackheads, whiteheads and irregular texture.
Mandelic Acid
An alpha-hydroxy acid with exfoliating and complementary antimicrobial properties.
It supports surface renewal while helping refine uneven texture associated with oily and acne-prone skin.
Shikimic Acid
A naturally derived acid highlighted by Mesoestetic as one of the key actives in blemiderm® Treatment.
It provides complementary exfoliating and sebum-regulating activity within the formula's multi-acid strategy.
blemiclear Complex
Mesoestetic's proprietary acne-regulation technology.
The brand positions blemiclear complex around four key actions:
Sebum regulation
Microbiota rebalancing
Anti-inflammatory activity
Regulation of hormonal pathways associated with blemish formation
The manufacturer does not map the complete trade complex to one single ingredient on the consumer product page, so Chris&Alley does not present blemiclear as though it were an individual INCI ingredient.
Sphingomonas Ferment Extract
A biotechnology-derived ferment included in the current formula.
It provides skin-conditioning support and fits within the product's broader microbiome-conscious approach.
Epigallocatechin Gallate
A potent green-tea-derived antioxidant.
EGCG provides antioxidant and anti-inflammatory support and complements the formula's strategy for inflamed, blemish-prone skin.
Serenoa Serrulata Fruit Extract
Saw Palmetto extract is included within the current formulation and provides complementary support within the product's oil-regulating strategy.
Bioflavonoids
Plant-derived antioxidant compounds that provide additional environmental and anti-inflammatory support.
Full Ingredient List:
Aqua, Dipropylene Glycol, Disodium Azelate, Caprylic/Capric Triglyceride, Propanediol, Ethoxydiglycol, Alcohol Denat., Polyacrylate Crosspolymer-6, Salicylic Acid, Mandelic Acid, Shikimic Acid, Sphingomonas Ferment Extract, Epigallocatechin Gallate, Bioflavonoids, Serenoa Serrulata Fruit Extract, Phosphatidylcholine, Cholesterol, Isostearyl Alcohol, Retinol, Tocophersolan, 1,2-Heptanediol, Butylene Glycol, Glycerin, Ethylhexylglycerin, Arachidyl Alcohol, Butylene Glycol Cocoate, Behenyl Alcohol, Arachidyl Glucoside, Xanthan Gum, Mannitol, Ethylcellulose, Hectorite, Hydroxyethylcellulose, Poloxamer 338, Poloxamer 235, Polysorbate 20, Disodium EDTA, BHA, BHT, Sodium Benzoate, Potassium Sorbate, Phenoxyethanol.
Use once daily in the evening.
Apply to clean, completely dry skin over the face.
Avoid the eye contour and mucous membranes.
Allow the product to absorb before applying any compatible moisturising or recovery product if required.
Mesoestetic recommends discontinuing use if significant irritation develops.
Every morning, apply a high-protection broad-spectrum sunscreen — preferably SPF 50+.
Oily skin
Active acne
Recurring inflammatory blemishes
Blackheads and whiteheads
Persistent congestion
Excess sebum
Enlarged-looking pores
Thickened or irregular skin texture
Acne-prone skin requiring intensive correction
Post-acne uneven texture
Clients following the professional blemiderm® programme
Clients who need more intensive treatment than blemiderm® resurfacing gel
By participating in our promotions, customers agree to adhere to these terms and conditions. It is advised to review these terms regularly, as they may be subject to change without notice. If you have any questions or concerns, please contact our customer support team.
Very Good
Very Good
I've been using the mesoestetic acne one for a few years. The only product that ever made a difference to my ecsma prone forehead. This cream feels levelled up, very happy.
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It's a thing of beauty.
At Chris & Alley®, we redefine everyday beauty through professional-grade skincare, curated experiences, and unmatched service— online and in-store.
🤩 Fantastic! Will definitely buy again.
🤩 Fantastic! Will definitely buy again.
🤩 Fantastic! Will definitely buy again.
The service was excellent and the package arrived beautifully wrapped with a personal note. It smelled fantastic. The whole experience was an absolute treat.