Nicotinamide – Vitamin B3
Nicotinamide is the amide form of Vitamin B3 and is distinct from Nicotinic Acid / Niacin.
Within Acnevelle Plus AP⁴, it forms one of the central nutritional components for problematic skin.
Nicotinamide supports:
Normal skin function + skin-barrier health + a balanced inflammatory response + overall skin condition.
Lamelle specifically incorporates it into Acnevelle for acne-prone skin experiencing visible redness, irritation and excessive oiliness.
For Chris & Alley, I would avoid promising that oral Nicotinamide alone will:
Cure acne
or
Prevent every future breakout.
Better:
Provides complementary nutritional support for clearer-looking, acne-prone skin.
Zinc Picolinate
The current AP⁴ formula uses Zinc Picolinate, replacing the Zinc Glycinate described on the existing Chris & Alley page.
Zinc is an essential trace mineral involved in numerous normal physiological functions, including normal skin and immune function.
Within Acnevelle Plus AP⁴, Zinc is incorporated specifically to support:
Problematic skin + oil balance + normal skin function.
The current detailed AP⁴ specification lists:
50mg Zinc Picolinate providing 10mg elemental Zinc
although the current physical pack should remain the final reference for exact nutritional values.
Selenium
The key addition to the newer AP⁴ formulation.
Selenium is an essential trace mineral involved in antioxidant defence.
It supports normal antioxidant systems that help protect cells against oxidative stress.
For customer-facing copy, use:
Provides antioxidant support
rather than promising:
Repairs damaged tissue
or
Prevents skin ageing.
Current detailed AP⁴ specifications list an ingredient quantity designed to provide approximately:
100µg elemental Selenium
per declared serving/unit specification.
Because online wording around the Selenium raw-material weight is inconsistent, use the current pack's nutritional table for the final numerical declaration.
Copper
Copper has been deliberately included alongside Zinc.
Long-term higher Zinc intake can interfere with Copper absorption in some circumstances.
Adding Copper therefore helps support an appropriate mineral balance during ongoing supplementation.
Current AP⁴ information identifies the Copper source as:
Copper Sulphate
rather than the Copper Glycinate listed on the older Chris & Alley product description.
Current detailed product information indicates a quantity providing approximately:
0.5mg elemental Copper
per declared serving/unit specification.
Again, the physical product label should be used as the final source for mandatory nutritional values.

Take according to the instructions printed on the current Acnevelle Plus AP⁴ packaging or as directed by your healthcare professional.
Current AP⁴ retail guidance commonly recommends:
Take 2 caplets daily with a meal.
Take consistently at approximately the same time each day.
Do not exceed the recommended dose unless specifically advised by an appropriate healthcare professional.
Important
There is conflicting current online information regarding an older loading protocol of:
4 caplets daily for the first 2 weeks → followed by 2 daily.
Because the current Lamelle AP⁴ webpage does not publish a dosing schedule, the directions printed on the current physical AP⁴ pack should take precedence.

Pregnancy and Lactation

Acne-prone skin
Breakout-prone skin
Oily skin
Persistent blemishes
Mild-to-moderate inflammatory acne as part of an appropriate management plan
Skin prone to visible breakout-related redness
Excess oil production
Recurrent breakouts
Adult problematic skin
Teenage problematic skin where professionally appropriate
Clients already following the Lamelle Clarity programme
Clients seeking complementary nutritional support alongside topical skincare
Longer-term breakout-management programmes under appropriate guidance
Severe, cystic, painful or suddenly worsening acne should be professionally assessed rather than managed with supplements alone.