Patented Retinoic Acid Analogue – 3%
The defining active within RA 3.0.
Lamelle describes the formula as containing a 3% patented Retinoic Acid Analogue, while the published ingredient list identifies:
Hydroxypinacolone Retinoate
as the Vitamin A derivative.
This advanced retinoid supports:
Skin renewal + smoother texture + fine-line improvement + wrinkle correction + visible photoageing support.
For Chris & Alley, I would use the manufacturer wording:
3% patented Retinoic Acid Analogue
rather than calling it:
3% pure Retinol
because Hydroxypinacolone Retinoate is not the same molecule as Retinol.
Squalane
A lightweight skin-compatible emollient that helps soften the skin and support the lipid barrier.
Its inclusion is particularly useful within a retinoid formula because it helps maintain comfort and reduce an overly dry skin feel.
Avocado Oil
A nourishing botanical oil rich in skin-conditioning lipids.
It helps soften and replenish the skin while supporting the serum’s lipid-based delivery system.
Tetrahexyldecyl Ascorbate
A lipid-soluble Vitamin C derivative.
It provides complementary antioxidant support and helps support a brighter, healthier-looking complexion.
Because the formula already contains this Vitamin C derivative, there is no need to treat RA 3.0 as a simple single-active Retinoid serum.
4-T-Butylcyclohexanol
A skin-conditioning ingredient often used in formulations developed to support skin comfort and reduce sensations associated with irritation.
It complements the formula’s broader tolerability-focused design.
Caprylic/Capric Triglyceride
A lightweight emollient that helps support spreadability, softness and skin comfort.

Use in the evening only.
After cleansing, allow the skin to dry completely.
Apply approximately 2–3 small pea-sized drops directly to the skin using the dropper.
Massage gently over the:
Face + Neck
until evenly distributed.
Allow the serum to absorb, then follow with a non-retinoid night cream.
Do not layer another Retinol or retinoid-containing moisturiser over RA 3.0.
The following morning:
Cleanse → Moisturiser if required → Broad-spectrum SPF 50+
Consistent daytime sun protection is essential when incorporating retinoids into your routine.
If You Are New to Retinoids
Introduce gradually:
2–3 evenings per week → alternate evenings → nightly use according to tolerance.
If dryness, persistent redness or irritation develops, reduce application frequency until the skin has adjusted.

Pregnancy due to RA ester

All skin types
Early-to-moderate visible ageing
Fine lines
Wrinkles
Uneven or rough skin texture
Photoaged skin
Loss of skin resilience
Dull or tired-looking skin
Skin showing signs of sun-related ageing
Clients introducing an advanced retinoid treatment
Clients wanting a non-prescription Vitamin A serum
Clients progressing beyond basic anti-ageing skincare
Evening treatment routines